Importance of Time Lapses in Death of a Salesman :: English Literature

Why does Arthur Miller use time lapses in his play â€Å"Death of a Salesman†? What was the playwright trying to tell us about Willy Loman? In this essay I will be exploring and analysing â€Å"Death of a Salesman† by Arthur Miller. I will be looking the use of flash backs in the play that aim to emphasise that the past is always with us. Looking at the flashbacks will also help understand the character of Willy Loman. The action takes place in Willy Loman’s house and yard also in various places he visits in New York and Boston of 1949. The play was set in post war America. This is after the great Depression, when people had a different point of view and wanted to achieve the â€Å"American Dream†. The American Dream is the longings of people who wanted to develop the country, to amass money and enjoy a comfortable, not to be at the beck and call of the employer. The figure of a salesman was at the cutting edge of the American Dream, a self made person that did not sell his products but his personality. The play shows a series of chronological events which take place during one evening and the next day. At intervals throughout the play we see scenes from Willy’s past enacted on the same stage at the same time. On first impression this would seem more likely to confuse the audience rather than reveal, but Miller had strong reasons for staging the play in this way. It is my belief that playwright tells us the past is not something which is now behind us. The past is always with us informing and influencing our actions. To understand the character of Willy Loman, we must be aware of the emotional burdens he carries with him from the past. To show an example of these recollections I have selected a scene in Act Two. Willy is sitting in a restaurant where he has been invited by the boys, in anticipation of the fact that Biff will be able to secure a loan from Bill Oliver. Willy has just been laid off from his old job, and is hoping that Biff has some good news for him so that Linda can be happy as he knows she has always been loyal to him and made many sacrifices. Willy said â€Å"she has waited and she has suffered†. This shows how loyal and hard working Linda has been to the family, sacrificing to save money. Evidence of this is shown by the stockings that she sits down with and mends so money can be saved.

Meditech Organization and Systematic Issues Essay

1. What are Meditech’s problems in introducing new products? In manufacturing ALL products? Meditech was continuously turning its products obsolete by introducing new products. Every time a new product was introduced it resulted in serious supply problems, which in turn resulted in the dissatisfaction of customer due to poor service resulting from each product introduction. The variation of production schedules was often higher than variation in demand. Another problem was monthly forecasting that was the base of determining assembly schedules and parts orders. 2. What is driving these problems, both systematically and organizationally? The driver of the problem was the way to determine the production planning and scheduling. The Material Requirement Plan (MRP) system, which determines assembly schedules and part orders was based on three components one of them is the monthly forecast which was an erroneous approach. Customer Service and Distribution department could not figure out why Meditech consistently had shortages with each product introduction. Their distribution system was decentralized; the information existed on many systems in several different areas of the organization which make it even more difficult to realize what the problems were. 3. Why is the customer service manager the first person to recognize major issues? Customer services deals with everything from occasional customer complaints to establishing strategies to improve delivery to customers. Customer service department noticed that customers were becoming tired of the poor service resulting from each introduction. Through many meetings with hospital material managers, they began to realize about its customer’s frustrations when handling new products. 4. How would you fix these problems? The demand of any product is higher during the introduction stage and growth stage after that the demand of that same product will decrease during the maturity stage, therefore the supply could also be reduced so they won’t experiment surplus. As the book suggested I would change the method of planning production schedules. Instead of using monthly forecasting they should use more simple statistical methods. 5. Relate the learning of this case to a similar supply chain with which you are familiar? I’m familiar with a different industry that can experiment supply and demand differences, it is the case of restaurant distributors. Certain foods such as fruits and vegetables become obsolete in a very short period of time, so the distributors may get a lost if they don’t receive orders from restaurants, that is the reason why if there is an unexpected increase in demand they must be ready and have a back up or find a way to supply their customers, or else the distributors can lose customers. Restaurants on the other hand might have ten customers one day and seventy the next day so they also need a prestigious supplier to rely on in the case of sudden demand.

Trial Of DMXB-A in Schizophernia - Free Essay Example

Sample details Pages: 2 Words: 552 Downloads: 7 Date added: 2019/10/10 Did you like this example? Dimethoxybenzylidene which is abbreviated as DMXB-A is a drug is administered orally. It helps improve neuropsychological and attention in schizophrenia, hence an improved psychological outcome. There were three teams which were in the production of the drug and they were exploratory development team, project development team, clinical development and brand development team. They were tasked with discovery research, exploratory and full development, filling, launching and growth and maintenance. The major team was the clinical development team whose main roles were developing a clinical development plan, manage its execution and compiling the clinical portion of the regulatory submission in form of a case report form (CRF). There are two models under study design. These are traditional model and Innovative/adaptive model. Traditional model is further divided into phase 1,2,and3. Phase 1, the drug safety and tolerability must be established. One has to start with no-effect dose then later on take maximally tolerated dose. The dose range of cover 3-5 fold difference. During the initial stages single dose is recommended but between 5-7 days, multiple dose is advised.   Under phase 2 is further subdivided into phase 2a and phase 2b, the sample size is usually above 50 patients depending on the state of the disease. Its duration is between 1-5 year and studies conducted on patients and volunteers. Don’t waste time! Our writers will create an original "Trial Of DMXB-A in Schizophernia" essay for you Create order Phase 2a which also known as pilot studies. Its initial step also is to determine the safety, efficacy and tolerability in patients, tolerated dose range in patients is also established. Thereafter evaluation is done on relevant biomarkers and pharmacokinetic parameters in patients. Estimation of degree of variation is also essential. Proof of concept states that the drug must demonstrate right pharmacology, appropriate therapeutic index and reach intended target and intended tissues. It should also be enriched with collection of data such as plasma and genomic (Meyer et al.). Adaptive trial uses accumulating data from ongoing study. Its advantage is that it increases the likelihood of selecting phase 3 dose and it use more ethical treatment considerations. The early phase of adaptive trial is to find safe and effective dose while the later phase makes prospective changes to future trials. The traditional plan of adaptive design takes a duration of 16-22 week whereby SAD (4-5 dose) and MAD (3-4 dose) are administered. While modified adaptive design takes a duration of 12-18 weeks. Phase 2b one determines the dose range and level of phase 3 while confirming the its primary endpoints and estimating treatment effects. Phase 3 includes pivotal trials which generate clinically and statistically significant evidence. It involves thousands of patients and takes a span of 3.5 years. It was noted that between 2011 and 2015 that on a single pivotal, 50 % of new drug approvals were made (Sagineedu et al.). Treatment groups were Experimental Therapy groups and control groups. Pompe disease showed that 70-80 % of children die as a result of cardiac failure before they attain the age of 1 year. In a case study carried out, it was found that in the treatment of Parkison’s disease by use of antidepressants, 65 % of the patients improved through active drug treatment. In the double-blind study, the percentage of the patients who improved were only 20%. In an early study carried out, it showed that recombinant GAA helped improve cardiac, survival and respiratory functions. It was concluded that patients who received rhGAA had 90% survival chances and were free from ventilation